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Hello from The AI Night,
Today in AI:
A Tech Guy Cures His Dog's Cancer by Uploading Its DNA to ChatGPT
Anthropic Doubles Claude Usage Limits During Off-Peak Hours
Nebius Signs AI Infrastructure Agreement With Meta Worth upto $27B
Here's the deal: Sydney tech entrepreneur Paul Conyngham used ChatGPT to brainstorm immunotherapy options, then applied AI tools to analyze genomic data and design a personalized mRNA cancer vaccine for his rescue dog Rosie, diagnosed with advanced mast cell cancer in 2024.
The Breakdown:
Conyngham paid $3,000 to get Rosie's healthy and tumor DNA sequenced at UNSW's Ramaciotti Centre for Genomics, then used AI pipelines and AlphaFold to identify mutations, map mutated proteins and match potential drug targets.
UNSW's RNA Institute manufactured the bespoke mRNA vaccine based on Conyngham's half-page formula. Rosie received her first injection in December 2025.
One tennis ball-sized tumor has roughly halved in size. Researchers call it the first personalized mRNA cancer vaccine designed for a dog.
A second vaccine targeting a non-responsive tumor is now in development, with new genetic sequencing underway.
The bigger picture: This case demonstrates how AI tools can compress complex genomic analysis into workflows accessible to skilled non-biologists. UNSW researchers say the approach directly informs their work on personalized mRNA treatments for human cancer patients.
Here's the deal: Anthropic is running a limited-time promotion that doubles five-hour usage limits for Claude users outside peak weekday hours. The promotion runs from March 13 through March 27, 2026, and applies automatically with no action required.
The Breakdown:
Usage is doubled outside 8 AM to 2 PM ET on weekdays. Peak-hour limits stay the same.
Eligible plans include Free, Pro, Max, and Team. Enterprise plans are excluded.
The bonus usage does not count against weekly usage limits on any plan.
The promotion covers Claude on web, desktop, mobile, Cowork, Claude Code, Claude for Excel, and Claude for PowerPoint.
No changes to billing or plan settings. Once the promotion ends, limits revert to standard levels.
The bigger picture: This is a load-balancing play disguised as a user perk. Anthropic is incentivizing users to shift heavy workloads off-peak, smoothing demand on its infrastructure while reducing peak-hour congestion. For builders, it is free extra capacity. Strategically, it builds off-peak usage habits that could support long-term capacity planning.
Here's the deal: Nebius Group, the Amsterdam-based AI cloud company, announced a 5 year AI infrastructure supply agreement with Meta worth up to approximately $27 billion. The deal covers dedicated GPU capacity built on one of the first large-scale deployments of the NVIDIA Vera Rubin platform.
The Breakdown:
Nebius will provide $12 billion in dedicated capacity across multiple locations, with delivery starting early 2027.
Meta has also committed to purchasing up to $15 billion in additional available compute across upcoming Nebius clusters over five years.
Nebius currently plans to sell that additional capacity to third-party AI cloud customers, with Meta purchasing remaining unused capacity.
The deal is built on NVIDIA's Vera Rubin platform, positioning Nebius among the first to deploy it at scale.
Nebius's 2026 guidance remains unchanged despite the announcement.
The bigger picture: This is one of the largest single AI infrastructure contracts announced to date, signaling that hyperscalers like Meta are increasingly turning to specialized AI cloud providers rather than building everything in-house. For Nebius, it validates the company's full-stack AI cloud model and secures long-term revenue visibility through 2032.
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What else you need to know:
Microsoft Research released GigaTIME, a multimodal AI that converts cheap H&E pathology slides into virtual tumor immune images, generating 300,000 scans across 14,256 cancer patients from routine clinical data.
Moonshot AI introduced Attention Residuals, replacing fixed residual connections with learned, input-dependent cross-layer attention, validated on a 48B-parameter model with a 1.25x compute advantage.
Ziphu AI launched GLM-5-Turbo, a faster variant of its GLM-5 model optimized for agent-driven environments now available via OpenRouter and its own API.
xAI's Grok Imagine ranked first for video editing on Design Arena, enabling users to edit scenes and add, remove or swap objects and characters via its API.
Niantic used over 30 billion real-world images collected via Pokémon Go to build a visual navigation dataset now powering GPS-free location recognition for delivery robots.
Aman Gottumukkala, founder of a widely used Android coding agent scaled to millions in revenue is joining xAI and SpaceX to build coding AI.
Tsinghua University and Galbot researchers introduced LATENT, a framework that trains humanoid robots to play tennis using imperfect human motion fragments, enabling real-world multi-shot rallies on the Unitree G1.
That’s it for today’s edition of The AI Night.
Our goal is to cut through the noise, surface what actually changed, and explain why it matters.
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